com.claidex/failure-intelligence
Official24 toolsClaidex MCP
Biomedical failure intelligence platform for terminated trials and translational analysis.
Biomedical failure intelligence for terminated trials and translational analysis.
Captured live from the server via tools/list.
claidex_capabilities
Return the Claidex MCP feature map, configured storage/model providers, safety controls, resources, prompts, and tool counts.
No parameters.
claidex_claim_risk_matrix
Search claims and summarize MRS bands, trial phases, failure archetypes, and high-risk programs for rapid diligence.
Parameters (2)
- querystringrequired
Drug, target, disease, sponsor, or failure archetype.
- limitintegerrequired
claidex_health_snapshot
Return Sentinel metrics, coverage, graph counts, recent automation runs, MRS bands, and preprint-watch summaries.
No parameters.
claidex_research_prompt
Compose a rigorous, reusable investigation prompt that tells an MCP client which Claidex tools and resources to use.
Parameters (4)
- objectivestringrequired
The investigation objective to turn into a reusable MCP prompt.
- target_genestring
Optional HGNC target symbol.
- diseasestring
Optional disease area.
- risk_tolerancestringrequired
claidex_tool_catalog
Return the complete MCP tool catalog, optionally including full input schemas and filtering native versus agent-backed tools.
Parameters (2)
- include_schemasbooleanrequired
Include full JSON Schemas in the catalog.
- sourcestringrequired
consult_specialist_model
Ask a specialist Gateway model for code, database/tool-calling, statistics, literature, preprint, or mechanistic synthesis support. Use for hard subproblems, second opinions, code generation/review, or complex synthesis.
Parameters (3)
- task_typestringrequired
Specialist routing target.
- promptstringrequired
Focused task for the specialist model.
- contextstring
Relevant context, snippets, or data. Do not include secrets.
fetch
Fetch a specific result returned by search. This compatibility tool supports OpenAI and ChatGPT remote MCP retrieval flows.
Parameters (1)
- idstringrequired
Result id returned by the search tool.
fetch_research_url
Fetch a public HTTPS research URL, JSON API response, package metadata endpoint, documentation page, or dataset preview. Blocks private/internal hosts and truncates large responses.
Parameters (2)
- urlstringrequired
Public HTTPS URL to fetch.
- max_charsnumberrequired
get_claim_content
Retrieve the complete text content of a specific Claidex Claim by its slug. Use this when you need to read the full post-mortem analysis, including hypothesis, failure mechanism, and prevention analysis.
Parameters (1)
- slugstringrequired
The Claidex claim slug, e.g. exicorilant-mcrpc-gr-bypass-fourth-failure
query_chembl
Look up a drug or compound in ChEMBL. Returns mechanism of action, primary target, ChEMBL ID, max development phase, molecular type, and synonyms.
Parameters (1)
- drug_namestringrequired
Drug or compound name
query_clinicaltrials
Search ClinicalTrials.gov for clinical trials. Can search by drug name, condition, target, or NCT ID. Returns trial status, phase, sponsor, primary endpoints, and why_stopped if terminated.
Parameters (4)
- querystringrequired
Search term: drug name, condition, NCT ID, or target
- statusstringrequired
- phasestringrequired
- max_resultsnumberrequired
query_failure_graph
Query the Claidex failure graph for a specific gene target. Returns the Mechanism Risk Score (MRS), failure counts by phase and archetype, and all related claim slugs.
Parameters (1)
- target_genestringrequired
HGNC gene symbol, e.g. PIK3CA, KRAS, EGFR
query_openfda
Query the FDA FAERS database for adverse event signals for a drug. Returns top adverse event terms, serious case count, and death count.
Parameters (2)
- drug_namestringrequired
Drug name as it appears in FAERS
- max_resultsnumberrequired
query_opentargets
Query Open Targets for target-disease association evidence. Returns genetic evidence score, clinical evidence, known drugs, tractability, and safety liabilities for a gene-disease pair.
Parameters (2)
- target_genestringrequired
HGNC gene symbol
- disease_termstringrequired
Disease name or EFO term
query_package_registry
Look up package metadata from npm or PyPI before recommending code, analysis packages, API clients, or dataset tooling.
Parameters (2)
- ecosystemstringrequired
Package registry to query.
- package_namestringrequired
Package name.
rank_documents_by_embedding
Embed a query and candidate documents, then rank documents by cosine similarity. Use for semantic matching, retrieval checks, clustering triage, and lightweight RAG over user-provided passages.
Parameters (3)
- querystringrequired
- documentsarrayrequired
- top_knumberrequired
rerank_documents
Rerank candidate documents/passages against a query using a dedicated reranking model. Use after retrieval/search when exact relevance ordering matters.
Parameters (3)
- querystringrequired
- documentsarrayrequired
- top_nnumberrequired
run_computation
Evaluate deterministic mathematical expressions with optional variables. Use for algebra, matrices, vectors, transformations, descriptive numerical checks, and reproducible calculations. Does not execute arbitrary JavaScript or install packages.
Parameters (2)
- expressionstringrequired
MathJS expression, e.g. mean(values), std(values), multiply(A, b), inv(A).
- variablesobjectrequired
Variables available to the expression. Values must be numbers, strings, vectors, or matrices.
run_statistical_analysis
Run a statistical analysis computation. Supports: Wilson confidence intervals, binomial proportions, phase transition success rates, power calculations, Bayesian posterior estimates, descriptive statistics, and two-proportion comparisons. Returns computed values, interpretation, and LaTeX formula.
Parameters (3)
- analysis_typestringrequired
- inputsobjectrequired
Named input parameters. wilson_ci: {successes, n, confidence}. phase_transition_rate: {phase, indication, n_succeeded, n_total}. power_calculation: {n, effect_size, alpha}. bayesian_posterior: {prior_success_rate, n_observed, n_success, prior_strength?}. descriptive_stats: {values: number[]}. failure_rate_comparison: {a_success, a_n, b_success, b_n}.
- contextstring
Optional context about what this analysis is for
search
Search Claidex failure claims and preprint flags. This compatibility tool returns citation-ready results for OpenAI and ChatGPT remote MCP flows.
Parameters (2)
- querystringrequired
Biomedical failure intelligence query.
- limitintegerrequired
search_claims
Search the Claidex failure database for post-mortems matching a drug name, gene target, disease, failure archetype, or sponsor. Returns matching claims with title, slug, drug, target, disease, phase, failure archetype, Open Targets score, and MRS score.
Parameters (4)
- querystringrequired
Search term: drug name, gene symbol, disease, or failure archetype
- categorystringrequired
- failure_archetypestringrequired
- limitnumberrequired
search_preprint_flags
Search the Claidex Preprint Watch database for bioRxiv preprints flagged as contradicting the clinical failure record. Search by target gene, disease, or preprint title.
Parameters (2)
- querystringrequired
Search term: gene symbol, disease, or preprint title fragment
- severitystringrequired
search_pubmed
Search PubMed for biomedical literature. Returns title, authors, journal, year, DOI, abstract, and PMID for each result.
Parameters (2)
- querystringrequired
PubMed search query
- max_resultsnumberrequired
web_search
Search the web for recent news, investor commentary, analyst notes, press releases, and conference coverage about drugs, clinical trials, or biomedical mechanisms.
Parameters (2)
- querystringrequired
Search query
- focusstringrequired
README not available yet.
Install
Configuration
CLAIDEX_MCP_URLdefault https://app.claidex.com/api/mcpClaidex MCP endpoint URL.
CLAIDEX_MCP_API_KEYrequiredsecretClaidex API key for protected tools and resources.
claude_desktop_config.json
{
"mcpServers": {
"failure-intelligence": {
"command": "npx",
"args": [
"-y",
"@claidex-mcp/claidex-mcp@1.0.0"
],
"env": {
"CLAIDEX_MCP_URL": "https://app.claidex.com/api/mcp",
"CLAIDEX_MCP_API_KEY": "<YOUR_CLAIDEX_MCP_API_KEY>"
}
}
}
}