io.github.pubspro/pharma-mcp

Official

by pubspro

MCP server for ClinicalTrials.gov, PubMed, FDA drug labels, FAERS, and ICH guidelines.

Access clinical trials, medical literature, drug labels, and regulatory guidelines data.

Topics

ai-agentclaudeclinicaltrialsfdahealthcaremcpmedical-writingmodel-context-protocolpharmapubmed

README.md4 KBView on GitHub

pharma-mcp

MCP server for clinical and pharmaceutical data.

Gives Claude and any MCP-compatible AI agent direct access to:

ClinicalTrials.gov — search and retrieve trial protocols, endpoints, eligibility criteria
PubMed — literature search with MeSH terms, full abstracts, citation formatting
FDA openFDA — drug labels, approved indications, warnings, boxed warnings
FDA FAERS — adverse event reports with patient demographics and outcomes
ICH Guidelines — structured summaries of E3, E6, E9, M4, Q1A, and more

No API keys required. All data sources are public. Runs locally in under 60 seconds.

Tools

Tool	Description
`search_clinical_trials`	Search ClinicalTrials.gov by condition, drug, or sponsor
`get_trial_details`	Full protocol details by NCT ID
`search_pubmed`	PubMed literature search with MeSH, Boolean, date filters
`get_pubmed_abstract`	Full abstract + metadata by PMID
`search_fda_drugs`	FDA drug label search — indications, warnings, dosage forms
`get_fda_adverse_events`	FAERS adverse event reports by drug and/or reaction
`get_ich_guideline`	ICH guideline summaries by code (E3, E6, M4…) or topic
`format_citation`	Vancouver, APA, or AMA citation from a PMID

Quickstart

Install

bash

git clone https://github.com/pubspro/pharma-mcp.git
cd pharma-mcp
npm install

Add to Claude Desktop

Edit ~/Library/Application Support/Claude/claude_desktop_config.json (macOS) or %APPDATA%\Claude\claude_desktop_config.json (Windows):

json

{
  "mcpServers": {
    "pharma-mcp": {
      "command": "node",
      "args": ["/absolute/path/to/pharma-mcp/src/index.js"]
    }
  }
}

Restart Claude Desktop. The tools appear automatically.

Add to Claude Code

bash

claude mcp add pharma-mcp node /absolute/path/to/pharma-mcp/src/index.js

Example prompts

Once connected, ask Claude:

code

Search ClinicalTrials.gov for Phase 3 recruiting trials for non-small cell lung cancer involving osimertinib.

code

Find the 10 most recent PubMed papers on GLP-1 receptor agonists and cardiovascular outcomes. Format citations in Vancouver style.

code

Get the FDA label for semaglutide — what are the boxed warnings and contraindications?

code

What does ICH E3 require for a clinical study report? Which sections are mandatory?

code

Pull adverse event reports for dupilumab involving anaphylaxis from FAERS.

Use cases

Medical writers and publications teams

Rapid literature gap analysis for advisory boards and manuscripts
Auto-format reference lists from PubMed searches
Check ICH E3 requirements mid-draft without switching tabs

Regulatory affairs

Search FDA labels for labeling precedent
Check FAERS signal for benefit-risk narratives
Retrieve ICH guideline requirements for CTD modules

Clinical development

Competitive landscape searches across ClinicalTrials.gov
Identify comparable trial designs and endpoints

AI agent pipelines

Chain pharma-mcp tools with other MCP servers for autonomous regulatory research workflows

Data sources

All data retrieved in real time from official public APIs — no data stored, no API keys required:

Requirements

Node.js 18+
npm

Roadmap

EMA EPAR search
DailyMed full prescribing information
GPP4 / ICMJE authorship criteria checker
ClinVar genetic variant lookup

PRs and issues welcome.

License

MIT

Install

claude_desktop_config.json

{
  "mcpServers": {
    "pharma-mcp": {
      "command": "npx",
      "args": [
        "-y",
        "@pubspro/pharma-mcp@1.0.0"
      ]
    }
  }
}